Our search for a new broad spectrum bactericide for preserving materials lead to the discovery of a highly active bicyclic amine (1) and a number of derivatives. The synthesis and biological evaluation as well as a first toxicological assessment of these compounds are described. Compound 1 shows strong bactericidal activity down to levels of below 100ppm but unfortunately increases the number of mutations in Ames tests.
![4H-Cyclopent[c]isoxazol-3-amine, 5,6-dihydro- Structure](https://image.chemsrc.com/caspic/354/698975-77-8.png)
