Abstract Application of the SAMP-/RAMP-hydrazone method offers an efficient and flexible access to compounds with a quaternary stereogenic center. Examples bearing silyl, thio, phenyl, aldo, keto, ester, and alkyl functionalities are described. The 2-phenylaldehydes and- ketones and the β-keto esters 4 were obtained in good overall yields and with variable enantiomeric excesses. The synthesis of the thiolated 2-formyl and 3-formyl carboxylic ...
