Results Synthesis of Sulfhydryl Reducing Agents. All of the characteristics of DTT as a reagent for reducing disulfide moieties are satisfactory except for its expense. A solution to the problem of providing an effective, inexpensive reducing agent could come either from a reduction in the cost of DTT, or by developing an alternative, easily prepared, material having comparable properties. DTT is prepared from 1, 4-dibromo-2-butene by a four-step ...
