The synthesis of 4??(3, 3??dimethyl??3H??pyrrolo [2, 3??f] quinolin??2??yl) pyrazoles and 4??(3, 3??dimethyl??3H??pyrrolo [3, 2??h] quinolin??2??yl) pyrazoles

A Rashidi, A Afghan, MM Baradarani…

Index: Rashidi; Afghan; Baradarani, Mehdi M.; Jouleb, John A. Journal of Heterocyclic Chemistry, 2009 , vol. 46, # 3 p. 428 - 431

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Citation Number: 15

Abstract

We recently described the reaction of 2, 3, 3-trimethylindolenines (3H-indoles) 1 with the Vilsmeier reagent formed from dimethylformamide and phosphorus oxychloride to produce aminomethylene malondi-aldehydes 2 [1, 2]. Additionally, we showed that these intriguing polyfunctional compounds reacted well with hydrazine or arylhydrazines to produce 4-(3, 3- dimethyl-3H-indol-2-yl)-substituted pyrazoles, 3, with migration of the double bond into the ...