Synthetic Communications®

Triton B–mediated mild, convenient, and efficient method for the selective alkylation of cyclic secondary amines and thiols

HM Meshram, BC Reddy, PR Goud

Index: Meshram; Reddy, B. Chennakesava; Goud, P. Ramesh Synthetic Communications, 2009 , vol. 39, # 13 p. 2297 - 2303

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Citation Number: 16

Abstract

There are numerous methods for the N-alkylation of cyclic secondary amines. Traditionally, alkylation has been performed using alkyl halides in an organic solvent in the presence of a base. Metal amides have also been used as base for the alkylation in the presence of an excess of ...