e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Novel thiophene-based macrocycles related to azacrown ethers
…, JDE Chaffin, J Halfpenny, PR Huddleston…
Index: Barker, John M.; Chaffin, Julie D. E.; Halfpenny, Joan; Huddleston, Patrick R.; Tseki, Potlaki F. Journal of the Chemical Society, Chemical Communications, 1993 , # 23 p. 1733 - 1734
A range of compounds containing two 3-oxygenated thiophene rings linked through the oxygen atoms by a variety of alkyl and heteroalkyl chains has been prepared and subjected to electrophillic substitution, at C (2) and C (2′), giving,, bis-Mannich bases containing 14- to 22-membered rings; preliminary X-ray diffract