ABSTRACT The synthesis, characterization and photophysical properties of two perfluoroalkyl (5, 10, 15, 20-tetrakis-[trifluoromethyl]-and [heptafluoropropyl]-porphyrin) and two perfluoroaryl (5, 10, 15, 20-tetrakis-[2, 6-difluorophenyl]-and [pentafluorophenyl]- porphyrin) are described, with reference to their potential in both photodynamic therapy (PDT) and in vivo imaging by fluorescence and 19 F nuclear magnetic resonance ...