Design and synthesis of novel 2-amino-5-hydroxyindole derivatives that inhibit human 5-lipoxygenase

J Landwehr, S George, EM Karg…

Index: Cocco; Congiu; Maccioni; Plumitallo; Schivo; Palmieri Farmaco, Edizione Scientifica, 1988 , vol. 43, # 1 p. 103 - 112

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Citation Number: 40

Abstract

... Volume: Page: ... still significantly inhibited 5-LO, although somewhat less potent as compared to the parental compounds (Table 1). Therefore, the ... the exact potency of those compounds that showed significant inhibition of 5-LO activity at 10 μM, selected ...