Bromamine-B/PdCl2 is an Efficient System for the Synthesis of Anthranilic Acids from Indoles and Indigos

…, KN Shivananda, CN Raju, RV Jagadeesh

Index: Kumar, C. Vinod; Shivananda; Raju, C. Nagu; Jagadeesh Synthetic Communications, 2010 , vol. 40, # 23 p. 3480 - 3487

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Citation Number: 4

Abstract

A convenient method has been developed for the conversion of indoles and indigos into anthranilic acids in good to excellent yields using a bromamine-B/PdCl2 system. The general process utilizes our efficient method for the oxidation of indoles and indigos in alkaline (pH 12) acetonitrile/water (1: 1) at 60° C.