Abstract Acridine-modified oligodeoxyribonucleotides (ODNs) at the C5-position of a 2′- deoxyuridine via different lengths of linker arms were synthesized. Reaction of 5-(N- aminoalkyl) carbamoylmethyl-2′-deoxyuridines with 9-phenoxyacridine gave the acridine- modified 2′-deoxyuridines which were incorporated into ODNs. The duplexes containing the acridine-modified strands and their complementary DNA or RNA were thermally more ...