The ubiquitous cytochrome P-450 isozymes are heme-thiolate enzymes, which function as oxygen-activating components in monooxygenase systems. They play a vital role both in the construction and destruction of cellular substances, catalyze the oxidative metabolism of lipophilic xenobiotics,"] activate vitamins, and convert a range of chemical compounds into carcinogens in the course of chemical cancerogenesis.['I Under anaerobic conditions 0 ...
