A structure–activity relationship study of 1, 2, 4-triazolo [1, 5-a][1, 3, 5] triazin-5, 7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated …

H Bera, BJ Tan, L Sun, AV Dolzhenko, WK Chui…

Index: European Journal of Medicinal Chemistry, , vol. 67, p. 325 - 334

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Citation Number: 14

Abstract

... European Journal of Medicinal Chemistry. ... 2,4-Triazolo[1,5-a][1,3,5]triazine, a fused heterobicyclic system, constitutes an important contribution in medicinal chemistry. ... 2,4-triazoles as illustrated in Scheme 1. The adopted synthetic method is based on the chemistry developed by ...