Anti-influenza diarylheptanoids from the bark of Alnus japonica

NH Tung, HJ Kwon, JH Kim, JC Ra, Y Ding…

Index: Tung, Nguyen Huu; Kwon, Hyuk-Joon; Kim, Jae-Hong; Ra, Jeong Chan; Ding, Yan; Kim, Jeong Ah; Kim, Young Ho Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 3 p. 1000 - 1003

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Citation Number: 29

Abstract

This study to investigate anti-influenza components from the bark of Alnus japonica resulted in the isolation of two rare acylated diarylheptanoids, named oregonoyl A (5) and oregonoyl B (6), along with nine known compounds (1–4 and 7–11). Their structures were elucidated on the basis of extensive spectroscopic and chemical methods. Antiviral testing of compounds 1–11 against KBNP-0028 (H9N2) avian influenza virus showed that ...