… of Aqueous Polyethylene Glycol on 1, 3??Dipolar Cycloaddition of Benzoylnitromethane/Ethyl 2??Nitroacetate with Dipolarophiles: Green Synthesis of Isoxazoles and …

…, A Raghunadh, T Krishna, S Mukherjee…

Index: Chary, R. Gangadhara; Reddy, G. Rajeshwar; Ganesh; Prasad, K. Vara; Raghunadh, Akula; Krishna; Mukherjee, Soumita; Pal, Manojit Advanced Synthesis and Catalysis, 2014 , vol. 356, # 1 p. 160 - 164

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Citation Number: 13

Abstract

Abstract: A 1: 1 mixture of water-polyethylene glycol (PEG) facilitated the 1, 3-dipolar cycloaddition of benzoylnitromethane/ethyl 2-nitroacetate with terminal alkynes or alkenes leading to isoxazoles or isoxazolines under green conditions. The methodology is free from the use of any base, catalyst, dehydrating agent or hazardous solvent. Keywords: cycloaddition; isoxazoles; isoxazolines; PEG; polyethylene glycol; water