Tetrahedron letters

CsF in organic synthesis. The first and convenient synthesis of enantiopure bisoprolol by use of glycidyl nosylate

K Kitaori, Y Furukawa, H Yoshimoto, J Otera

Index: Kitaori, Kazuhiro; Furukawa, Yoshiro; Yoshimoto, Hiroshi; Otera, Junzo Tetrahedron Letters, 1998 , vol. 39, # 20 p. 3173 - 3176

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Citation Number: 17

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The regioselective substitution of glycidyl nosylate with phenols is catalyzed by CsF in the presence of K 2 CO 3 in DMF; this reaction enables the first and convenient synthesis of enantiopure bisoprolol. ... The first synthesis of enantiopure (S)-bisoprolol was achieved by use of a ...