Normally, 'click reactions' are efficient but time-consuming. Microwave heating, at controlled temperature and pressure may considerably reduce reaction time without promoting any side reactions. Thus, the synthesis of 1,4-disubstituted 1,2,3-triazoles under microwave irradiation may be a suitable alternative. [¹8] It features consecutive chemical transformation of alkyl halide to alkyl azide and subsequently to 1,2,3-triazoles, all in one pot. ... One-pot sequential multi- ...
