2, 2, 2-Trichloroethylsulphonyl, 2, 2, 2-trichloroethoxysulphonyl, and trifluoroacetyl isocyanates in β-lactam synthesis

AGM Barrett, A Fenwick, MJ Betts

Index: Barrett, Anthony G. M.; Fenwick, Ashley; Betts, Michael J. Journal of the Chemical Society, Chemical Communications, 1983 , # 6 p. 299 - 301

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Abstract

Condensation of the title isocyanates with olefins and subsequent dissolving-metal reduction (sulphonyl derivatives) or chromatography on Florisil (trifluoroacetyl derivatives) gave several N-unsubstituted β-lactams including two 8-aza-2-oxabicyclo [4.2. 0] octan-7- one derivatives.