Abstract With the purpose to synthesize novel ADAs (adenosine deaminase) and IMPDH (inosine 5′-monophosphate dehydrogenase) inhibitors the reaction of 5-amino-1-tert-butyl- 1H-pyrrolo-3-carbonitrile with fluorinated 1, 3-biselectrophiles was studied. An efficient and convenient synthetical approach to obtain fluorinated pyrrolo [2, 3-b] pyridines was developed. tert-Butyl protecting group was successfully cleaved by treating of synthesized ...
![1-(TERT-BUTYL)-4,6-BIS(TRIFLUOROMETHYL)-1H-PYRROLO[2,3-B]PYRIDINE-3-CARBONITRILE Structure](https://image.chemsrc.com/caspic/338/1146221-73-9.png)