Proton??ionizable crown compounds. 9. Synthesis and structural studies of new 14??crown??4 compounds containing a pyridine or 4??pyridone subcyclic unit

JS Bradshaw, JM Guynn, SG Wood…

Index: Bradshaw; Guynn; Wood; et al. Journal of Heterocyclic Chemistry, 1987 , vol. 24, # 2 p. 415 - 419

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Citation Number: 14

Abstract

Abstract Four new 14-crown-4 macrocyclic ligands containing either a pyridine or a 4- pyridone subcyclic unit have been prepared. Two of the 4-pyridono-crowns contained lipophilic hydrocarbon substituents. The starting octyl-and benzyl-substituted 4-oxa-1, 7- heptanediols were prepared from the 2-octyl-or 2-benzyl-1, 3-propane-diol. When the two substituted 4-oxa-1, 7-heptanediols were treated with tosyl chloride, both the expected 2- ...