A chloro-containing chiral β-amino alcohol (S)-2-amino-3-(2-chlorophenyl)-1, 1-diphenyl-1- propanol (1) was prepared from the related amino acid, which was synthesized via malonic ester method. As a catalyst for the enantioselective borane reduction of prochiral ketones, 1 is better than those that have a similar structure but have no halogen atom in the molecule.
