Journal of combinatorial chemistry

Iodine-promoted domino reaction leading to N-substituted 2-aminoquinoline-3-carbonitriles under microwave irradiation

B Jiang, C Li, SJ Tu, F Shi

Index: Jiang, Bo; Hao, Wen-Juan; Zhang, Jin-Peng; Tu, Shu-Jiang; Shi, Feng Organic and Biomolecular Chemistry, 2009 , vol. 7, # 6 p. 1171 - 1175

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Citation Number: 24

Abstract

A new iodine-promoted domino reaction of 2-aminochromene-3-carbonitriles with various isocyanates is described, and a set of polyfunctionalized N-substituted 2-aminoquinoline-3- carbonitriles with high regioselectivity were successfully synthesized under microwave

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