Synthesis

Highly efficient and clean method for direct α-iodination of aromatic ketones

G Yin, M Gao, N She, S Hu, A Wu, Y Pan

Index: Yin, Guodong; Gao, Meng; She, Nengfang; Hu, Shengli; Wu, Anxin; Pan, Yuanjiang Synthesis, 2007 , # 20 p. 3113 - 3116

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Citation Number: 34

Abstract

Abstract Under neutral reaction conditions, aromatic ketones were transformed into the corresponding α-iodo ketones in high yields by the combination of copper (II) oxide and iodine. The reaction mechanism showed that copper (II) oxide played multiple roles through random self-sorting.