A green preparation of N-chloro-and N-bromosaccharin

…, JFM da Silva, MCS de Mattos

Index: De Souza, Soraia P. L.; Da Silva, Joaquim F. M.; De Mattos, Marcio C. S. Synthetic Communications, 2003 , vol. 33, # 6 p. 935 - 939

Full Text: HTML

Citation Number: 27

Abstract

The reaction of the sodium salt of saccharin, potassium chloride or bromide and oxone® in water at room temperature for 24 h produced pure N-chloro- and N-bromosaccharin in 58% and 64% yield, respectively. ... The reaction of the sodium salt of saccharin, potassium chloride or bromide and oxone® in water at room temperature for 24 h produced pure N-chloro- and N-bromosaccharin in 58% and 64% yield, respectively. ... Although N-halosaccharins are more electrophilic ...