Tetrahedron

Synthesis of multivalent N-acetyl lactosamine modified quantum dots for the study of carbohydrate and galectin-3 interactions

Y Yang, XC Xue, XF Jin, LJ Wang, YL Sha, ZJ Li

Index: Yang, Yang; Xue, Xiao-Chao; Jin, Xiao-Feng; Wang, Li-Jun; Sha, Yin-Lin; Li, Zhong-Jun Tetrahedron, 2012 , vol. 68, # 35 p. 7148 - 7154

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Citation Number: 9

Abstract

Ternary core/shell CdSeS/ZnS-QDs coated with N-acetyl lactosamine was prepared as a fluorescent probe to study the interactions of N-acetyl lactosamine and galectin-3. The synthesis of N-acetyl lactosamine was achieved through the 'azidoiodoglycosylation'method. The amount of ligand coated on QDs was determined by 1H NMR and ICP-OES. The interactions between carbohydrates and galectin-3 were measured using SPR. The ...