Synthesis of benzyloxybromobenzonitriles

…, M Anbazhagan, CE Stephens, DW Boykin

Index: Ismail, Mohamed A.; Anbazhagan, Mariappan; Stephens, Chad E.; Boykin, David W. Synthetic Communications, 2004 , vol. 34, # 5 p. 751 - 758

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Citation Number: 3

Abstract

As part of an anti??infective drug discovery research program we needed to synthesize several different triaryl systems consisting of one or more hydroxy??substituted benzamidine groups. As these benzamidine??based triaryl systems are typically prepared by palladium??catalyzed Stille or Suzuki couplings with a substituted bromobenzonitrile, we required hydroxy??protected bromocyanophenols as precursors.11. Tidwell , RR and Boykin , DW 2003. “Dicationic DNA minor groove ...