Synthesis and pharmacological studies of N-substituted 6-[(2-aminoethyl) amino]-1, 3-dimethyl-2, 4 (1H, 3H)-pyrimidinediones, novel class III antiarrhythmic agents

T Katakami, T Yokoyama, M Miyamoto…

Index: Journal of Medicinal Chemistry, , vol. 35, # 18 p. 3325 - 3330

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Citation Number: 13

Abstract

... Synthesis, 1981,l-28. 324, 781-788. 0 1992 American Chemical Society Page 2. 3326 Journal of Medicinal Chemistry, 1992, Vol. 35, No. 18 Katakami et al. Scheme I X QOCH~CH-CH (Method A) '0' 6 EtOH I : Y E: OCH,CHCH, 16 - 18 11 Y = O(CH2)n 19-31,33 ...