Organic letters

Chemoenzymatic dynamic kinetic resolution of allylic alcohols: A highly enantioselective route to acyloin acetates

K Bogár, PH Vidal, AR Alcántara León…

Index: Martin-Matute, Belen; Bogar, Krisztian; Edin, Michaela; Kaynak, F. Betuel; Baeckvall, Jan-E. Chemistry - A European Journal, 2005 , vol. 11, # 20 p. 5832 - 5842

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Citation Number: 52

Abstract

Dynamic kinetic resolution (DKR) of a series of sterically hindered allylic alcohols has been conducted with Candida antarctica lipase B (CALB) and ruthenium catalyst 1. The optically pure allylic acetates obtained were subjected to oxidative cleavage to give the