2-Aryl-3, 6-dialkyl-5-dialkylaminopyrimidin-4-ones as novel crf-1 receptor antagonists

KJ Hodgetts, T Yoon, J Huang, M Gulianello…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 15 p. 2497 - 2500

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Citation Number: 14

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... 1 The diversity of chemical matter among leading series is rather narrow, particularly considering the compounds which reached advanced preclinical development or clinical stage (eg, topology 1: CP-154,526, R121919, DMP 904 ...