Δ2??Isoxazolines from β, γ??unsaturated oximes

…, LG Emmerich, KS Frost, B Anderson

Index: Mosher, Michael D.; Emmerich, Laura G.; Frost, Katherine S.; Anderson, Benjamin Journal of Heterocyclic Chemistry, 2006 , vol. 43, # 3 p. 535 - 539

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Citation Number: 16

Abstract

3, 5-Disubstituted 2-isoxazolines can be prepared using the palladium-mediated nucleometalation/methoxycarbonylation of β, γ-unsaturated oximes. This novel route to this class of compounds is tolerant of a wide variety of functionality in the starting material, and provides a rapid route to highly functionalized isoxazolines.