Abstract The molecular and crystal structure of 1, 3, 3, 5-tetraphenylpentane-1, 5-dione (I) obtained from direct methods and anisotropically refined by the least-squares method shows that the two 3, 3-phenyl groups force the molecule into a conformation suitable for formation of cyclic products and intermediates. Compound I crystallizes in P1 group with lattice parameters a= 8.444 (1), b= 10.195 (2), c= 14.618 (2) Å, α= 75.52 (2), β= 73.22 (1), γ= ...