Organic letters

Solventless Clay-Promoted Friedel-Crafts Reaction of Indoles with α-Amido Sulfones: Unexpected Synthesis of 3-(1-Arylsulfonylalkyl) Indoles

R Ballini, A Palmieri, M Petrini, E Torregiani

Index: Ballini, Roberte; Palmieri, Alessandro; Petrini, Marino; Torregiani, Elisabetta Organic Letters, 2006 , vol. 8, # 18 p. 4093 - 4096

Full Text: HTML

Citation Number: 81

Abstract

Friedel-Crafts reaction of indoles with α-amido sulfones in the presence of montmorillonite K- 10 leads unexpectedly to 3-(1-arylsulfonylalkyl) indoles in good yield. The obtained products can be further desulfonylated under reductive or alkylative conditions giving linear and ...

~83%

An efficient route to 2, 3-disubstituted indoles via reducti...

[Cao, Liang-Liang; Wang, Duo-Sheng; Jiang, Guo-Fang; Zhou, Yong-Gui Tetrahedron Letters, 2011 , vol. 52, # 22 p. 2837 - 2839]

Total synthesis of (+)-isatisine A

[Arcari, Marinella; Aveta, Raffaele; Brandt, Alberto; Cecchetelli, Loredana; Corsi, Giordano Bruno; Rella, Mario Di Gazzetta Chimica Italiana, 1991 , vol. 121, # 11 p. 499 - 504]

Selective Ruthenium??Catalyzed Alkylation of Indoles by Usin...

[Imm, Sebastian; Baehn, Sebastian; Tillack, Annegret; Mevius, Kathleen; Neubert, Lorenz; Beller, Matthias Chemistry - A European Journal, 2010 , vol. 16, # 9 p. 2705 - 2709]