Journal of the American Chemical Society

The Mechanism of Addition of Grignard Reagents to Ketones

CG Swain, HB Boyles

Index: Swain; Boyles Journal of the American Chemical Society, 1951 , vol. 73, p. 870

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Citation Number: 65

Abstract

Discussion.-The compounds were tested in vitro as antagonists of the growth of Staphylococcus aureus, using Klinger medium and of Escherichia coli, using MacLeod medium. The organisms were inoculated, at the peak of their growth curves, into Klett- Summerson tubes containing standard drug concentrations. The tubes were incubated at 37'for 24 hours, and growth was determined by means of a Klett-Summerson photoelectric ...