Bacillus subtilis ypgA gene is fni, a nonessential gene encoding type 2 isopentenyl diphosphate isomerase

…, K Kaneda, T Shimizu, Y Hayakawa…

Index: Takagi, Motoki; Kaneda, Kazuhide; Shimizu, Tomohiro; Hayakawa, Yoichi; Seto, Haruo; Kuzuyama, Tomohisa Bioscience, Biotechnology and Biochemistry, 2004 , vol. 68, # 1 p. 132 - 137

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Citation Number: 26

Abstract

We previously identified the fni gene of Streptomyces sp. strain CL190 as type 2 isopentenyl diphosphate (IPP) isomerase, which needs both FMN and NADPH for enzyme activity. An fni gene homolog, ypgA, was detected in the database of the Bacillus subtilis genome. However, the ypgA product was about 140 amino acids shorter in the N-terminal than the Streptomyces fni gene product. A database search found three new putative start codons ...