N??Tosylhydrazones as Reagents for Cross??Coupling Reactions: A Route to Polysubstituted Olefins

J Barluenga, P Moriel, C Valdés…

Index: Barluenga, Jose; Moriel, Patricia; Valdes, Carlos; Aznar, Fernando Angewandte Chemie - International Edition, 2007 , vol. 46, # 29 p. 5587 - 5590

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Citation Number: 189

Abstract

Pd-catalyzed cross-coupling reactions can be considered nowadays to be the most reliable methodology for the formation of C (sp2) ÀC (sp2) bonds.[1] These types of reactions find increasing application in the synthesis of complex organic molecules.[2] In a cross-coupling reaction, an electrophile is combined with a nucleophile to provide the corresponding coupling product (Scheme 1 a). Organometallic reagents such as organomagnesium,[3]- ...