Transaminations of enaminones: A Synthesis of tricyclic, N??aryl, 1, 2, 3??triazole??fused pyridones

…, R Friary, H Jones, JH Schwerdt, V Seidl…

Index: Chan, Tze-Ming; Friary, R.; Jones, H.; Schwerdt, J. H.; Seidl, V.; et al. Journal of Heterocyclic Chemistry, 1990 , vol. 27, # 4 p. 1135 - 1142

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Citation Number: 5

Abstract

Abstract 1-Phenylmethyl-and 1-(4-methoxyphenylmethyl)-5-chloro-1, 2, 3-triazole-4- carbonyl chlorides acylated the pyrrolidine enamines of cyclopentanone and cyclohexanone, and the resulting enaminones underwent transaminations with aryl amines under acidic conditions. The products then cyclized under basic conditions to linearly fused, tricyclic 3-phenylmethyl-and 3-(4-methoxyphenylmethyl)-4-aryl-8-oxo-4, 5, 6, 7- ...