An improved procedure for the preparation of 1??benzyl??1H??1, 2, 3??triazoles from benzyl azides

…, D Hands, PG Houghton, GR Humphrey…

Index: Cottrell, Ian F.; Hands, David; Houghton, Peter G.; Humphrey, Guy R.; Wright, Stanley H. B. Journal of Heterocyclic Chemistry, 1991 , vol. 28, # 2 p. 301 - 304

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Citation Number: 41

Abstract

Abstract A procedure for the preparation of substituted 1-benzyl-1H-1, 2, 3-triazoles from benzyl azides under very mild conditions is described. The method provides improved yields and extends the scope of the Dimroth Reaction to other types of active methylene compound to those previously used. Benzyl azides react with active methylene compounds in dimethyl sulphoxide catalysed by potassium carbonate at 35–40 to give 1H-1, 2, 3-triazoles usually ...