Analogues of the anticonvulsant agent milacemide (1, 2-(n-pentylamino) acetamide), in which the carboxamide group is changed to a nitrile (21, a carbethoxy group (3), a carboxylic acid (4), a cyanomethyl group (S), and a trifluoromethyl group (61, were synthesized and tested as substrates and inactivators of monoamine oxidase B (MA0 B). The carboxylic acid was neither a substrate nor an inactivator. The trifluoromethyl ...
