Journal of Heterocyclic Chemistry

Microwave??assisted one??pot synthesis of functionalized pyrimidines using ionic liquid

DS Raghuvanshi, KN Singh

Index: Raghuvanshi, Dushyant Singh; Singh, Krishna Nand Journal of Heterocyclic Chemistry, 2011 , vol. 48, # 3 p. 582 - 585

Full Text: HTML

Citation Number: 10

Abstract

Abstract An efficient one-pot multicomponent synthesis of 2, 4-diamino-5- pyrimidinecarbonitrile derivatives has been achieved in excellent yields by the condensation of aromatic aldehydes, malononitrile, and guanidine using ionic liquid under controlled microwave irradiation (100 W) at 60 C. This green approach offers a number of advantages in terms of methodology, high-product yield, short reaction time, mild reaction conditions, ...