Abstract New piperazinyl amidrazones have been synthesized by direct interaction of the corresponding aryl hydrazones with the appropriate piperazine. On the basis of preliminary screening data for these new compounds, the antitumor activity of 1-(4-methylpiperazin-1-yl)- 1, 2-propandione 1-[2-(4-chlorophenyl) hydrazone] and 1-(4-ethylpiperazin-1-yl)-1, 2- propandione 1-[2-(4-chlorophenyl) hydrazone] was evaluated. Mean 50% growth ...
