e.g. Filippa Pettersson or Cancer Res. 75(6) , 1102-12, (2015) or 10.1002/anie.201600521
Kinetics of reactions of hydroxide ion and water with. beta.-X-substituted. alpha.-nitrostilbenes (X= Cl, I, SEt, OMe, SCH2CH2OH) in 50% Me2SO-50% water. Search …
CF Bernasconi, J Fassberg, RB Killion Jr…
Index: Bernasconi, Claude F.; Fassberg, Julianne; Killion Jr., Robert B.; Schuck, David F.; Rappoport, Zvi Journal of the American Chemical Society, 1991 , vol. 113, # 13 p. 4937 - 4946
Abstract: The hydrolysis of Ph (LG) C= CPh (N02)(4-M, LG= CI, I, SEt, OMe) in basic solution yields the anion of 1, 2-diphenyl-2-nitroethanone, PhC (= O) C (= NO,-) Ph (83, by the addition-elimination mechanism of nucleophilic vinylic substitution (Scheme I), while the reaction of base with Ph (SCH2CH20H) C= CPh (N02)(4-SCH2CH20H) leads to a cyclic intermediate (T) by intramolecular nucleophilic attack by the ionized OH group (eq 6). The ...