Pd??Catalyzed Reactions of Allenylphosphonates and Related Allenes with Functionalized 2??Iodophenols, 2??Iodobenzoic Acid, and 2??Iodobenzyl Alcohol Leading to …

…, M Chakravarty, KC Kumara Swamy

Index: Phani Pavan; Chakravarty, Manab; Kumara Swamy European Journal of Organic Chemistry, 2009 , # 34 p. 5927 - 5940

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Citation Number: 32

Abstract

Abstract Regioselective, palladium-catalyzed coupling reactions of allenylphosphonates (OCH 2 CMe 2 CH 2 O) P (O) CH= C= CRR′[R, R′= H (1a), R= H, R′= Me (1b), R= R′= Me (1c)] and phenyl allenes PhCH= C= CR 2 [R= H (2a), Me (2b)] with functionalized iodophenols (in PEG-400), 2-iodobenzoic acid, and 2-iodobenzyl alcohol are investigated. Benzofurans with free aldehyde functionalities are formed in high yields (1 H/31 P NMR) ...