Abstract: Copper-catalyzed CÀX activation-phosphorylation of aryls bearing different groups has been achieved using P (O) ÀH compounds as efficient phosphorylation reagents without the assistance of any ligand. Optically active H-phosphinates can also act as good substrates in the reaction, giving the (Sp)-phosphoryl substituted phenolic compounds stereospecifically with retention of configuration at the phosphorus center. Furthermore, it ...
