Highly regioselective synthesis of trifluoromethyl derivatives of pyrazolo [1, 5-a] pyrimidines bearing fused cycloalkane rings using (2-ethoxycycloalkenyl)-2, 2, 2- …

…, SI Selivanov, YV Nelyubina, MY Antipin

Index: Emelina, Elena E.; Petrov, Aleksander A.; Selivanov, Stanislav I.; Nelyubina, Yulia V.; Antipin, Mikhail Yu. Journal of Fluorine Chemistry, 2009 , vol. 130, # 10 p. 861 - 869

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Citation Number: 6

Abstract

8-Trifluoromethyl-6, 7-dihydro-5H-1, 4, 8a-triaza-s-indacene and 9-trifluoromethyl-5, 6, 7, 8- tetrahydropyrazolo [5, 1-b] quinazolines were efficiently generated by condensation of 5 (3)- aminopyrazoles with (2-ethoxycycloalkenyl)-2, 2, 2-trifluoroethanones and isolated in ...