Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... A new route for the total synthesis of (±)-helminthosporal ((±)-1), involving fragmentation reaction of tricyclo[3.2.1.0 2,7 ]octane derivative 5 to give bicyclo[3.2.1]octane derivative 6 as a crucial step, is described. ... (±)-Helminthosporal, (±)-1, was synthesized stereoselectively from ...