The title ring system was synthesized for the first time by acid-promoted condensation of ureas with 1, 4-diformyl-2, 3, 5, 6-tetrahydroxypiperazine. Nitrosation and nitration of the polycycle occurs fit at the piperazine nitrogens. Succeseive further nitration leads to tetra-, penta-, and hexanitro derivatives. X-ray crystallographic analysis of the tetra-and hexanitm derivatives established the cis-syn-cis configuration and an all-axial conformation for this ...
![Octahydro-1,3,4,5,7,8-hexanitro-diimidazo[4,5-b:4',5'-e]pyrazine-2,6(1H,3H)-dione Structure](https://image.chemsrc.com/caspic/051/115029-33-9.png)