Synthesis, physicochemical properties, and biological evaluation of N-substituted 2-alkyl-3-hydroxy-4 (1H)-pyridinones: orally active iron chelators with clinical …

PS Dobbin, RC Hider, AD Hall, PD Taylor…

Index: Journal of Medicinal Chemistry, , vol. 36, # 17 p. 2448 - 2458

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Citation Number: 198

Abstract

... These bidentate ligands also 0022-2623/93/1836-2448$04.00/0 0 1993 American Chemical Society Page 2. ... The ex- perimental conditions ensured that the most associated species predominated. Journal of Medicinal Chemistry, 1993, Fe3+ + L- + FeL2+ ...