A new bis (3-hydroxy-4-pyridinone) derivative of iminodiacetic acid, imino-bis (acetyl (1-(3′- aminopropyl)-3-hydroxy-2-methyl-4-pyridinone)), IDAPr (3, 4-HP) 2, has been prepared and studied in its interaction with a set of hard metal ions. This tetradentate ligand presents a much higher chelating efficiency for trivalent hard metal ions (Fe, Ga, Al) than the monodentate derivative Deferriprone, namely at the diluted conditions prevailing in ...