Lead optimization of 4-acetylamino-2-(3, 5-dimethylpyrazol-1-yl)-6-pyridylpyrimidines as A2A adenosine receptor antagonists for the treatment of Parkinson's disease

X Zhang, JE Tellew, Z Luo, M Moorjani…

Index: Journal of Medicinal Chemistry, , vol. 51, # 22 p. 7099 - 7110

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Citation Number: 30

Abstract

... Journal of Medicinal Chemistry. ... Departments of Medicinal Chemistry, Pharmacology, Neuroscience, Chemical Development, Preclinical Development, and Pharmaceutical Development, Neurocrine Biosciences, 12780 El Camino Real, San Diego, California 92130 ...