Seven 3-methylidene-1H-indol-2 (3H)-ones related to the multiple-receptor tyrosine kinase inhibitor sunitinib

…, S Hamid, AP Mendham, L Male, SJ Coles…

Index: Spencer, John; Chowdhry, Babur Z.; Hamid, Samiyah; Mendham, Andrew P.; Male, Louise; Coles, Simon J.; Hursthouse, Michael B. Acta Crystallographica Section C: Crystal Structure Communications, 2010 , vol. 66, # 2 p. o71-o78

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Citation Number: 7

Abstract

The solid-state structures of a series of seven substituted 3-methylidene-1H-indol-2 (3H)- one derivatives have been determined by single-crystal X-ray diffraction and are compared in detail. Six of the structures {(3Z)-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-2 (3H)-one, C13H10N2O,(2a);(3Z)-3-(2-thienylmethylidene)-1H-indol-2 (3H)-one, C13H9NOS,(2b);(3E)- 3-(2-furylmethylidene)-1H-indol-2 (3H)-one monohydrate, C13H9NO2· H2O,(3a); 3-(1- ...