Reduction of carbonyl function to a methyl group

…, T Jin, K Matsuda, V Gevorgyan, Y Yamamoto

Index: Bajracharya, Gan B.; Nogami, Tsutomu; Jin, Tienan; Matsuda, Kumiko; Gevorgyan, Vladimir; Yamamoto, Yoshinori Synthesis, 2004 , # 2 p. 308 - 311

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Citation Number: 20

Abstract

Abstract A direct exhaustive reduction of aliphatic carbonyl functions (aldehydes, acyl chlorides, esters and carboxylic acids) to a methyl group by triethylsilane (Et 3 SiH) in the presence of catalytic amount of tris (pentafluorophenyl) borane [B (C 6 F 5) 3] is described. Aromatic carbonyl functions could undergo partial reduction to the corresponding TES- protected benzylic alcohols.